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  Term Curation Status    
 
1,4-benzodiazepinone
Published  
 

Definitionno definition provided for external entity

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4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol
Published  
 

DefinitionA member of the class of nitrosamines that is butan-1-ol substituted by a pyridin-3-yl group at position 1 and by a methyl(nitroso)amino group at position 4. It is a major metabolite of nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), which is a carcinogen found in tobacco and responsible for inducing lung cancer in smokers.

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4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one
Published  
 

Definition4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one (CHEBI:32692) is a nitrosamine (CHEBI:35803).

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abstinence duration
Published  
 

DefinitionA temporal interval during which a person is abstinent from a behaviour.

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abstinence from a behaviour
Published  
 

DefinitionA personal attribute in which a person does not engage in a behaviour during a time period.

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acetyl-amino acid
Published  
 

DefinitionAny amino acid derivative that is the <em>N</em>-acetyl or <em>O</em>-acetyl derivative of an amino acid.

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acetylcysteine
Published  
 

DefinitionA metabolite of acrolein and may be found in the urine of smokers.

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action specification
Published  
 

DefinitionA directive information entity that describes an action the bearer will take.

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addict identity
Published  
 

DefinitionA self-identity in which a person represents themselves as being addicted to something.

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addiction
Published  
 

DefinitionA mental disposition towards repeated episodes of abnormally high levels of motivation to engage in a behaviour, acquired as a result of engaging in the behaviour, where the behaviour results in risk or occurrence of serious net harm.

CommentThis entity focuses on extent of need to engage in a behaviour and includes potential serious net harm as a feature. The reason is to limit the class to things that merit a public health response. It is a quantitative dimension that may vary in severity and a fuzzy set because there can be varying thresholds set for degree of harm and strength of motivation. As a result, it is essential to operationalise the term for it to be meaningful.

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addictiveness
Published  
 

DefinitionA disposition of a material entity or a process to cause addiction to it.

CommentThis is a quantitative entity that is only meaningful when operationalised in terms of the proportion of people who are exposed who become addicted, the mode of use, the severity of addiction and any other contextual factors that may be in play. Addictiveness can be a disposition of material entity such as a chemical substance or a process such as gambling behaviour.

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additive
Published  
 

Definitiona role for a chemical additive to a mixture

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aetiopathogenetic role
Published  
 

DefinitionA role played by the molecular entity or part thereof which causes the development of a pathological process.

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affective appraisal
Published  
 

DefinitionA cognitive representation which represents an evaluation of the relevance of some triggering object or event to the organism.

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affective process
Published  
 

DefinitionA <mental process> that has positive or negative valence.

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